Lucas Weber
Principal Chemist
KPV
Product information
Product description
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone, Lys-Pro-Val. It retains the anti-inflammatory activity attributed to the parent hormone without its pigmentary action, which is why the fragment rather than the full sequence is used as a research probe. Requires reconstitution before use.
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KPV
- Characteristics
- How does KPV work?
- Research
- Safety & Handling
- Summary
- References
- Resource
- Peptonova Labs peptides
Characteristics
Molecular Formula | C16H29N3O4 |
CAS-number | 67727-97-3 |
Molar Mass | 327.42 g/mol |
Chemical Formula | Lys-Pro-Val |
Amino Acid Sequence | Lys-Pro-Val |
Synonyms | KPV tripeptide, α-MSH(11-13), KPV peptide |
Solubility | Water-soluble (≥1 mg/mL) |
Organoleptic Profile | White to off-white powder |
Composition | Lyophilized powder - requires reconstitution |
How does KPV work?
KPV is a tripeptide derived from α-melanocyte-stimulating hormone (α-MSH) that has been studied in scientific settings for its role in regulating inflammatory responses and immune system activity in non-human models.
Research
Research involving mammalian models has explored how KPV may influence certain biological processes: 1.Cytokine Response-Laboratory studies suggest KPV may affect the production of signaling molecules involved in inflammation. 2.Immune Modulation-Investigations have observed KPV's interaction with immune cells such as macrophages and T cells. 3.Melanocortin Pathways-KPV has been shown to activate specific receptors in controlled experiments, contributing to research into inflammation regulation.
Preclinical studies have examined KPV in the context of: Digestive tract balance, joint and connective tissue function, skin integrity and recovery, neurological research models, cellular regeneration processes.
Safety & Handling
This section describes laboratory handling. It is not clinical guidance, and no safety claim for human or veterinary administration is made or implied.
Supplied lyophilized. Reconstituted peptide solutions have materially shorter working stability than the dry powder — prepare working aliquots and avoid repeated freeze-thaw cycles.
Handle as a research chemical of undetermined hazard. Use gloves, eye protection and a laboratory coat.
Storage temperature and, where applicable, reconstitution conditions are stated on the item specification sheet and the lot Certificate of Analysis, which take precedence over general guidance.
Dispose of unused material and consumables in accordance with the institutional chemical waste policy.
For laboratory research use only. Not for human or veterinary use. Not a drug, food, cosmetic or dietary supplement.
Summary
KPV is a research peptide of scientific interest due to its observed activity in laboratory models, particularly those examining inflammatory and immune response mechanisms. While it has been evaluated in preclinical settings, KPV has not been reviewed or approved by regulatory bodies for medical or dietary use.
Disclaimer: This material is provided for informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. This product is intended strictly for laboratory research use and not for human or veterinary consumption.
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